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- Chemical formula – C20H16ClN5O2
- Molecular weight – 393.83
- Monoisotopic weight – 393.0992525
Other names:
- Testolone
- 1182367-47-0
- 4O87Q44KNC
- UNII-4O87Q44KNC
- RAD140 SARMs
- CHEMBL1672635
RAD-140 discovery:
RAD-140 belongs to the group of medications as Selective Androgenic Receptor Modulator (SARM). RAD-140 was discovered by a well-known company (pharmaceutical) as Radius Health Incorporation.
As per the medical applications, males have more secretion of testosterone in comparison to females. The testosterone hormone is responsible for the development of male traits and organs. Moreover, the same hormone is responsible for the development of male organs and physical characteristics such as muscle mass, build, and stature.
Mechanism of action:
RAD-140 Testolone resembles the action of drugs and hormones similar to testosterone, although it isn’t an absolute androgenic agent. Due to this property, Testolone may yield mass and strength benefits without causing side effects or any compromise to the user/individual.
The exact mechanism of action of Testolone is selective stimulation of the androgen receptors in the body. RAD-140 directly targets the different receptors in the muscles and bones without affecting the reproductive organs.
However, there aren’t any clear explanations about the SARMs and their selective activity on the receptors. A few pieces of evidence claim that SARMs affect proteins instead of testosterone. RAD-140 regulates the genes for androgen receptors. Moreover, RAD140 SARMs also suppresses the estrogen receptors as ESR1-mRNA. The overall effects of RAD-140 are to improve bone density and muscular strength in the body.
Applications of RAD-140:
Weight management:
RAD140 is a potential drug/supplement for weight management or weight loss. RAD-140 can directly improve the cholesterol levels in the body to initiate and assist weight loss. An increase in lean muscle mass can improve the body’s energy levels. Combined effects of RAD-140 help in faster metabolism and weight management in the body.
Anti-cancer effects:
As per a few research studies, RAD140 SARMs have some anti-cancer properties. Estrogen receptors are sensitive to the action of RAD-140. Therefore, this supplement can stop the growth of genes and cells in breast cancer. More specifically, RAD-140 can directly suppress the ESR1 gene action, which is the culprit for the production of estrogen receptors.
Increase in muscle mass:
RAD-140 has a popularity for its extraordinary effects in muscle building and bodybuilding. One benefit of using SARMs over other drugs is that RAD-140 can yield benefits and lean muscle mass increase without inflicting the body with any side-effect. Researchers also claim that RAD140 SAMRs can improve muscle mass just after one month of its administration.
Disclaimer:
The data provided in this article about RAD-140 Testolone has been written to provide knowledge for research advancement. It mainly aims to provide the best information to the emerging researchers who plan to study the benefits and effects of RAD140 SARMs. The article is specifically designed to provide information about RAD-140 rather than giving instructions about the use of it. Furthermore, there has been no mention of the dosage of the RAD-140 Testolone. The information provided in the article has been collected from different published researchers by a group of expert researchers keeping the medical protocols in view.
Furthermore, this article does not contain any information that will encourage the readers to consume or advertise RAD-140. We do not condone any advertisement of any supplement or drug that the FDA has not approved. Melanotan Express insists that no product should be ingested under any circumstances.
References:
- RAD140| 24428527/chemistry/Pubmed| https://pubmed.ncbi.nlm.nih.gov/24428527/
- RAD140| C20H16ClN5O2| Wikipedia https://en.wikipedia.org/wiki/RAD140Â
- RAD140 |DB13939 | Drugbank https://go.drugbank.com/drugs/DB13939
- Vasilev, V., & Boyadjiev, N. (2020). SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARM)-A NEW TEMPTATION IN SPORTS. TYPES, MODE OF ACTION AND SIDE EFFECTS OF THEIR APPLICATION. Journal of Applied Sports Sciences, (2), 107-115.
- Solomon, Z. J., Mirabal, J. R., Mazur, D. J., Kohn, T. P., Lipshultz, L. I., & Pastuszak, A. W. (2019). Selective androgen receptor modulators: current knowledge and clinical applications. Sexual medicine reviews, 7(1), 84-94.
- Vasilev, V., & Boyadjiev, N. (2021). Selective Androgen Receptor Modulators–Cellular, Tissue and Organ Selectivity. Asian Exercise and Sport Science Journal, 5(1), 20-33.
Where to find RAD-140 for Sale?
Melanotan Express offers RAD140 for sale with at least 99% purity. If you are looking to buy RAD-140 for research purposes, visit Melanotan Express, one of the leading online suppliers of the USA Peptides and SARMs for sale:
https://www.melanotanexpress.com/product/rad-140-10mg-ml-30ml/