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Product information:
Chemical formula – C1100H1646O314N294 S24
Molecular weight – 42749.8
Other names:
- GDF-8 (Growth Differentiation Factor 8)
- GDF8
- Myostatin
- MSTN
What Is Myostatin HMP?
Se-Jin Lee & Alexandra McPherron discovered the first Myostatin (MSTN) HMP in 1977.
MSTN is a protein known as GDF-8, which stands for Growth Differentiation Factor 8. Myostatin is widely found across muscle mass, typically produced by myocyte cells. It is evident to function as a muscle growth inhibitor. However, the two geneticists experimented on mice. The results proved Myostatin HMP to be a negative regulator of skeletal muscle growth.
How Does Myostatin Work?Â
Myostatin, a transforming growth factor, belongs to the beta-super-family. It binds to activin receptors (type 2) and starts a signaling cascade. It usually occurs through either Alk-3 or Alk-4 coreceptors. The signaling cascade triggers the activation of the SMAD family in muscles. The transcription factors, i.e., SMAD3 and SMAd2 of this family, induce Myostatin to precisely perform its functions, such as gene regulation or muscle protein breakdown.
Clinical Applications of Myostatin HMP:
Myostatin can be very beneficial. Some of its common clinical advantages include the following:
- Fat & Mass Regulation
Myostatin targets skeletal muscle tissues. Research claims that Myostatin is a compound encouraging negative regulation of muscle tissues. Even that actually became the reason for causing double muscle trait in cattle. It can also produce the double trait effect on mammals. Myostatin is very gleeful as it controls body fat mass. Consequently, promoting adipogenesis.
- Cardiac Development
Due to its negative muscle regulation, Myostatin plays a critical role in reverse remodeling after LVAD support. It causes heart failure, hypotrophy, and fibrosis. The experimental demonstrations on fetal and baby sheep have proved the theory.
If inactivated, Myostatin causes repression of AMP-activated kinase in the heart. It can further lead to cardiac hypertrophy or heart failure. Hence, Myostatin is significant. It helps prevent glycolysis switch and glycogen accumulation. In addition, the protein also maintains cardiac energy, preventing adverse developments.
- Energy Homeostasis Regulation
Skeletal muscle homeostasis is very crucial. It keeps the muscle function in balance. It also regulates stem cell activation and promotes the survival of muscle syncitia. Myostatin found there regulates energy homeostasis in the heart, ensuring no heart failure.
According to recent research, dogs with even a single myostatin gene excel in their overall performance.
Disclaimer:
The data provided in this article about Myostatin HMP has been written to provide knowledge for the research purposes only. The article is specifically designed to provide information about Myostatin HMP rather than giving instructions about the use of it. Furthermore, there has been no mention of the route of administration or dosage of the Myostatin Peptide. The information provided in the article has been collected from different published researchers by a group of expert researchers keeping the medical protocols in view.
Furthermore, this article does not contain any information to encourage readers to consume or advertise Myostatin HMP. We do not condone any advertisement of any supplement or drug that the FDA has not approved. Melanotan Express insists that no product should be ingested under any circumstances.
References:
- Sharma, Mridula, et al. “Myostatin in muscle growth and repair.” Exercise and sport sciences reviews4 (2001): 155-158.
- Glass, David J., and Bruce M. Spiegelman. “Se-Jin Lee, myostatin discoverer, elected to the National Academy of Science.” Skeletal Muscle1 (2012): 1-2.
- Myostatin | HMP|Science Direct|https://www.sciencedirect.com/topics/neuroscience/myostatin
- McPherron, Alexandra C., and Se-Jin Lee. “Suppression of body fat accumulation in myostatin-deficient mice.” The Journal of clinical investigation5 (2002): 595-601.
- Breitbart, Astrid, et al. “Myostatin from the heart: local and systemic actions in cardiac failure and muscle wasting.” American Journal of Physiology-Heart and Circulatory Physiology(2011).
- Elliott, Bradley, et al. “The central role of myostatin in skeletal muscle and whole body homeostasis.” Acta physiological 205.3 (2012): 324-340.
Where to find Myostatin for Sale?
If you are looking to buy Myostatin HMP (GDF8) for research purposes, visit Melanotan Express, one of the leading suppliers of the USA Peptides and SARMs for sale: https://www.melanotanexpress.com/product/myostatin-hmp-gdf8-1mg/